SCHEMBL1133477

SCHEMBL1133477

CC1=C(Cc2cccc(C)c2CC2=C(C)C(=O)NC2=O)C(=O)NC1=O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.34
AR P10275 2/20 0.34
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TAAR1 Q96RJ0 4/20 0.33
RXFP1 Q9HBX9 1/20 0.32
HTR1D P28221 1/20 0.31
ELANE P08246 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
CHRM2 P08172 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133697 0.83 ELANE (0.33) DAOELANE
SCHEMBL1132986 0.83 GSK3B (0.38) DAOARKDM4EELANEPTGS1
SCHEMBL21711979 0.81 HSD17B10 (0.32) KDM4EHSD17B10HTR1DALDH1A1
SCHEMBL3669618 0.79 DAO (0.34) DAOARKDM4EHSD17B10TAAR1
SCHEMBL168683 0.76 DAO (0.38) DAOKDM4E
SCHEMBL1133219 0.74 ESR1 (0.34) DAO
SCHEMBL1133470 0.74 TGM2 (0.33) DAO
SCHEMBL3676317 0.71 DAO (0.31) DAO
SCHEMBL1133158 0.71 DAO (0.34) DAOKDM4EALDH1A1
SCHEMBL3672110 0.70 GSK3B (0.37) DAOKDM4ETAAR1ELANEGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718699-B2 Rubber-steel cord composite and pneumatic tire using the same TOYO TIRE CORPORATION (JP) 2023-08-08 US disclosed
US-20210388143-A1 RUBBER-STEEL CORD COMPOSITE AND PNEUMATIC TIRE USING THE SAME TOYO TIRE CORPORATION (JP) 2021-12-16 US disclosed
EP-2289710-B1 Pneumatic tire BRIDGESTONE CORP (JP) 2018-11-07 EP disclosed
US-9617404-B2 Rubber composition, conveyor belt rubber composition, conveyor belt, and belt conveyor device BRIDGESTONE CORPORATION (JP) 2017-04-11 US disclosed
EP-1297974-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2017-03-15 EP disclosed
US-20160122519-A1 RUBBER COMPOSITION, CONVEYOR BELT RUBBER COMPOSITION, CONVEYOR BELT, AND BELT CONVEYOR DEVICE BRIDGESTONE CORPORATION (JP) 2016-05-05 US disclosed
US-8672011-B2 Rubber composition for bead apex and tire having bead apex prepared using same SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-03-18 US disclosed
US-20130075010-A1 RUBBER COMPOSITION FOR BEAD APEX AND TIRE HAVING BEAD APEX PREPARED USING SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-03-28 US disclosed
US-8383711-B2 Rubber composition for tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-02-26 US disclosed
EP-2009049-B1 RUBBER COMPOSITION FOR BEAD APEX AND TIRE WITH BEAD APEX UTILIZING THE SAME SUMITOMO RUBBER IND (JP) 2012-11-14 EP disclosed
EP-2287015-A2 Pneumatic tire Bridgestone Corporation (JP) 2011-02-23 EP disclosed
US-20100224299-A1 RUBBER COMPOSITION FOR TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-09-09 US disclosed
US-20100175805-A1 RUBBER COMPOSITION FOR COVERING TEXTILE CORD AND TIRE EMPLOYING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-07-15 US disclosed
US-20090151844-A1 Rubber Composition for Bead Apex and Tire Having Bead Apex Prepared Using Same SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2009-06-18 US disclosed
EP-2009049-A1 RUBBER COMPOSITION FOR BEAD APEX AND TIRE WITH BEAD APEX UTILIZING THE SAME Sumitomo Rubber Industries, Ltd. (JP) 2008-12-31 EP disclosed
US-20060272760-A1 Pneumatic tire BRIDGESTONE CORPORATION 2006-12-07 US disclosed
US-20030088023-A1 Containing an alkylenebis(dithio-nitrogen cap) compound, a citraconimide compound, or an acrylate compound; suitable particularly for a reinforcing rubber for tire sidewall portions and for a tire bead filler rubber. BRIDGESTONE CORPORATION (JP) 2003-05-08 US disclosed
EP-1297974-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2003-04-02 EP disclosed
US-20030015272-A1 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-23 US disclosed
EP-1197518-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE WITH THE SAME BRIDGESTONE CORPORATION (JP) 2002-04-17 EP disclosed