SCHEMBL1133697

SCHEMBL1133697

CC1=C(Cc2cccc(CC3=C(C)C(=O)NC3=O)c2C)C(=O)NC1=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.33
PDK2 Q15119 1/20 0.32
GSK3B P49841 1/20 0.31
DAO P14920 1/20 0.31
PARP1 P09874 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132986 0.89 GSK3B (0.38) ELANEGSK3BDAO
SCHEMBL3676317 0.84 DAO (0.31) PDK2GSK3BDAO
SCHEMBL1133477 0.83 DAO (0.34) ELANEDAO
SCHEMBL21711979 0.80 HSD17B10 (0.32)
SCHEMBL168683 0.78 DAO (0.38) DAOPARP1
SCHEMBL1133158 0.76 DAO (0.34) GSK3BDAO
SCHEMBL3672110 0.76 GSK3B (0.37) ELANEGSK3BDAO
SCHEMBL907302 0.76 KMT2A (0.41) ELANEGSK3BDAO
SCHEMBL1133470 0.73 TGM2 (0.33) DAOPARP1
SCHEMBL1133219 0.73 ESR1 (0.34) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11230636-B2 Rubber composition having improved properties in the raw state and in the cooked state COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-01-25 US claimed
EP-3582977-B1 RUBBER COMPOSITION HAVING IMPROVED PROPERTIES IN THE RAW STATE AND IN THE COOKED STATE MICHELIN & CIE (FR) 2021-03-31 EP claimed
US-20200056017-A1 RUBBER COMPOSITION HAVING IMPROVED PROPERTIES IN THE RAW STATE AND IN THE COOKED STATE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-02-20 US claimed
WO-2018150136-A1 RUBBER COMPOSITION HAVING IMPROVED PROPERTIES IN THE RAW STATE AND IN THE COOKED STATE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-08-23 WO claimed
US-11718699-B2 Rubber-steel cord composite and pneumatic tire using the same TOYO TIRE CORPORATION (JP) 2023-08-08 US disclosed
WO-2023095850-A1 STEEL CORD-RUBBER COMPOSITE, MANUFACTURING METHOD FOR STEEL CORD-RUBBER COMPOSITE, AND TIRE 株式会社ブリヂストン 2023-06-01 WO disclosed
US-11230636-B2 Rubber composition having improved properties in the raw state and in the cooked state COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-01-25 US disclosed
US-20210388143-A1 RUBBER-STEEL CORD COMPOSITE AND PNEUMATIC TIRE USING THE SAME TOYO TIRE CORPORATION (JP) 2021-12-16 US disclosed
EP-3582977-B1 RUBBER COMPOSITION HAVING IMPROVED PROPERTIES IN THE RAW STATE AND IN THE COOKED STATE MICHELIN & CIE (FR) 2021-03-31 EP disclosed
WO-2020246527-A1 TRISULFIDE COMPOUND 住友化学株式会社 2020-12-10 WO disclosed
US-20200056017-A1 RUBBER COMPOSITION HAVING IMPROVED PROPERTIES IN THE RAW STATE AND IN THE COOKED STATE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-02-20 US disclosed
EP-2289710-B1 Pneumatic tire BRIDGESTONE CORP (JP) 2018-11-07 EP disclosed
US-20100175805-A1 RUBBER COMPOSITION FOR COVERING TEXTILE CORD AND TIRE EMPLOYING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-07-15 US disclosed
US-20090151844-A1 Rubber Composition for Bead Apex and Tire Having Bead Apex Prepared Using Same SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2009-06-18 US disclosed
EP-2009049-A1 RUBBER COMPOSITION FOR BEAD APEX AND TIRE WITH BEAD APEX UTILIZING THE SAME Sumitomo Rubber Industries, Ltd. (JP) 2008-12-31 EP disclosed
US-20060272760-A1 Pneumatic tire BRIDGESTONE CORPORATION 2006-12-07 US disclosed
US-20030088023-A1 Containing an alkylenebis(dithio-nitrogen cap) compound, a citraconimide compound, or an acrylate compound; suitable particularly for a reinforcing rubber for tire sidewall portions and for a tire bead filler rubber. BRIDGESTONE CORPORATION (JP) 2003-05-08 US disclosed
EP-1297974-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2003-04-02 EP disclosed
US-20030015272-A1 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-23 US disclosed
EP-1197518-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE WITH THE SAME BRIDGESTONE CORPORATION (JP) 2002-04-17 EP disclosed