SCHEMBL168683

SCHEMBL168683

CC1=C(Cc2cccc(CC3=C(C)C(=O)NC3=O)c2)C(=O)NC1=O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.38
PARP1 P09874 3/20 0.34
CYP19A1 P11511 2/20 0.33
TBXAS1 P24557 1/20 0.33
TGM2 P21980 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
IDH1 O75874 4/20 0.33
KDM4E B2RXH2 1/20 0.33
IL4I1 Q96RQ9 1/20 0.32
MEN1 O00255 1/20 0.32
PKM P14618 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL907302 0.87 KMT2A (0.41) DAOTBXAS1IDH1KDM4EMEN1
SCHEMBL1133158 0.84 DAO (0.34) DAOTBXAS1TGM2KDM4EMEN1
SCHEMBL3677368 0.84 XIAP (0.42) DAOMEN1KMT2A
SCHEMBL1133470 0.80 TGM2 (0.33) DAOPARP1TGM2
SCHEMBL1133219 0.80 ESR1 (0.34) DAOTGM2
SCHEMBL1133697 0.78 ELANE (0.33) DAOPARP1
SCHEMBL1132986 0.77 GSK3B (0.38) DAOKDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL1133477 0.76 DAO (0.34) DAOKDM4E
SCHEMBL27794707 0.74 MAOA (0.42) DAOPKMSMN1; SMN2
SCHEMBL3674394 0.71 DAO (0.36) DAOMEN1PKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4559967-B1 RUBBER MIXTURES CONTAINING AT LEAST ONE PROCESS AID OF FORMULA (I) LANXESS DEUTSCHLAND GMBH (DE) 2026-05-06 EP claimed
WO-2025108885-A1 RUBBER MIXTURES CONTAINING AT LEAST ONE PROCESSING AID OF FORMULA (I) LANXESS DEUTSCHLAND GMBH (DE) 2025-05-30 WO claimed
EP-4559967-A1 RUBBER MIXTURES CONTAINING AT LEAST ONE PROCESS AID OF FORMULA (I) LANXESS Deutschland GmbH (DE) 2025-05-28 EP claimed
WO-2025034218-A1 BETA RADIATION-RESISTANT ELASTOMERIC COMPOSITIONS, ARTICLES, AND METHODS THEREOF BARD PERIPHERAL VASCULAR, INC. (US) 2025-02-13 WO claimed
US-20240209192-A1 RUBBER COMPOSITION, RUBBER-METAL COMPOSITE, TIRE, HOSE, AND CRAWLER BRIDGESTONE CORPORATION (JP) 2024-06-27 US claimed
US-20240191060-A1 RUBBER MIXTURES CONTAINING N,N'-DIALKYL-P-PHENYLENEDIAMINES LANXESS DEUTSCHLAND GMBH (DE) 2024-06-13 US claimed
US-20240174802-A1 Build UP Film Curable Compositions AGC MULTI MAT AMERICA INC (US) 2024-05-30 US claimed
US-20240174623-A1 Build UP Film Curable Compositions AGC Multi Material America, Inc. 2024-05-30 US claimed
EP-4321349-A1 RUBBER COMPOSITION, RUBBER-METAL COMPOSITE, TIRE, HOSE, AND CRAWLER BRIDGESTONE CORPORATION (JP) 2024-02-14 EP claimed
EP-4313622-A1 RUBBER MIXTURES CONTAINING N,N?-DIALKYL-P-PHENYLENEDIAMINES LANXESS Deutschland GmbH (DE) 2024-02-07 EP claimed
US-6581660-B2 Antireversion agents of 1,3-bis(citraconimidomethyl)benzene and hexamethylene 1,6-bis(thiosulfate), disodium salt, dihydrate THE GOODYEAR TIRE & RUBBER COMPANY 2003-06-24 US claimed
US-20030015271-A1 Tire with rubber tread of cap/base construction wherein the tread base rubber composition contains combination of anti-reversion agents THE GOODYEAR TIRE & RUBBER COMPANY 2003-01-23 US claimed
US-20020173577-A1 Heat resistance at high speed DEEVERS SUSAN LYNN (US) 2002-11-21 US claimed
EP-1241213-A2 Tire with tread of rubber composition which contains 1,3-bis-(citraconimidomethyl) benzene or pentaerythritol triacrylate THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-09-18 EP claimed
US-20020088521-A1 Rubber composition for breaker cushion SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2002-07-11 US claimed
EP-1211282-A1 Rubber mix comprising expanded layer silicates ConiTech Holding GmbH (DE) 2002-06-05 EP claimed
EP-1207054-A1 Rubber composition for breaker cushion SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2002-05-22 EP claimed
EP-1197518-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE WITH THE SAME BRIDGESTONE CORPORATION (JP) 2002-04-17 EP claimed
EP-0988999-A2 Antireversion agent for inserts used in runflat tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-03-29 EP claimed
US-5623007-A CONTAINING ANTIREVERSION AGENT COMPRISING ZINC SALTS OF CARBOXYLIC ACIDS AND A BIS-CITRACONIMIDO COMPOUND KUMHO TIRE CO., LTD. (KR) 1997-04-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174623-A1 Build UP Film Curable Compositions CBX7, CBX4, CBX2 DAO 1560/4885PARP1 498/4885CYP19A1 1784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.