SCHEMBL11337306

SCHEMBL11337306

CCCOC(=O)c1c(N)oc(-c2ccccc2)c1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM6 O15303 3/20 0.58
ADORA3 P0DMS8 3/20 0.51
LMNA P02545 1/20 0.48
ALDH1A1 P00352 5/20 0.46
HPGD P15428 4/20 0.46
MAPT P10636 3/20 0.46
GAA P10253 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TSHR P16473 1/20 0.43
TP53 P04637 1/20 0.42
RAB9A P51151 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAOB P27338 1/20 0.42
PTGS2 P35354 1/20 0.42
PRNP P04156 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11494416 0.92 GRM6 (0.50) GRM6ADORA3LMNAALDH1A1HPGD
SCHEMBL11496756 0.82 GRM6 (0.54) GRM6LMNAALDH1A1HPGDMAPT
SCHEMBL11329491 0.74 GRM6 (1.00) GRM6ADORA3LMNAALDH1A1HPGD
SCHEMBL280167 0.72 ALDH1A1 (0.56) GRM6LMNAALDH1A1HPGDMAPT
SCHEMBL3942905 0.69 PRKCZ (0.68) GRM6LMNAALDH1A1HPGDMAPT
SCHEMBL7686721 0.68 ADORA3 (1.00) GRM6ADORA3LMNAALDH1A1HPGD
SCHEMBL9462 0.67 LMNA (0.79) LMNAALDH1A1HPGDMAPTMEN1
SCHEMBL21587530 0.67 PTGS1 (0.54) GRM6LMNAALDH1A1HPGDGAA
SCHEMBL22423696 0.67 ALDH1A1 (0.58) GRM6ADORA3LMNAALDH1A1MAPT
SCHEMBL28754871 0.67 ALDH1A1 (0.63) GRM6ADORA3LMNAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0004931-B1 USE OF DERIVATIVES OF FURAN AND THIOPHENE AS PLANT-GROWTH REGULATING AGENTS BAYER AG (DE) 1981-08-05 EP disclosed
US-4240820-A Method of regulating the growth of plants BAYER AKTIENGESELLSCHAFT (DE) 1980-12-23 US disclosed