Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337436 | 0.79 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2HSD17B10NPC1HPGD | |
| SCHEMBL11844094 | 0.75 | PDK1 (0.49) | MAPTSMN1; SMN2HSD17B10NPC1HPGD | |
| SCHEMBL11327579 | 0.75 | MEN1 (0.50) | MAPTSMN1; SMN2HSD17B10NPC1HPGD | |
| SCHEMBL11336225 | 0.73 | HPGD (0.46) | MAPTSMN1; SMN2HSD17B10NPC1HPGD | |
| SCHEMBL14735475 | 0.73 | ALDH1A1 (0.52) | ALDH1A1RAB9AUSP2TP53MEN1 | |
| SCHEMBL11520960 | 0.73 | MAPT (0.52) | MAPTSMN1; SMN2HSD17B10NPC1HPGD | |
| SCHEMBL11327576 | 0.73 | MAPT (0.57) | MAPTSMN1; SMN2HSD17B10NPC1HPGD | |
| SCHEMBL11841332 | 0.70 | HPGD (0.59) | MAPTSMN1; SMN2HSD17B10NPC1HPGD | |
| SCHEMBL11524981 | 0.70 | MAPT (0.50) | MAPTSMN1; SMN2HSD17B10NPC1HPGD | |
| SCHEMBL5832068 | 0.69 | ESR2 (0.49) | MAPTSMN1; SMN2HSD17B10NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265804-A | BENZOXAZOYLBENZOATES, OXADIAZOLE-2,5-DIBENZOATES, BENZOTRIAZOLES AND BENZOTRIAZOTRIAZOLES | EASTMAN KODAK COMPANY (US) | 1981-05-05 | — | — | US | claimed |
| US-4265804-A | BENZOXAZOYLBENZOATES, OXADIAZOLE-2,5-DIBENZOATES, BENZOTRIAZOLES AND BENZOTRIAZOTRIAZOLES | EASTMAN KODAK COMPANY (US) | 1981-05-05 | — | — | US | disclosed |