Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844094 | 0.82 | PDK1 (0.49) | SMN1; SMN2HPGDHSD17B10TP53NPC1 | |
| SCHEMBL11337433 | 0.79 | MAPT (0.43) | SMN1; SMN2HPGDHSD17B10TP53NPC1 | |
| SCHEMBL4728970 | 0.79 | ATM (0.55) | SMN1; SMN2HPGDTP53NPC1MAPT | |
| SCHEMBL11337441 | 0.78 | THRB (0.41) | SMN1; SMN2HPGDHSD17B10TP53NPC1 | |
| SCHEMBL5393391 | 0.77 | RXRA (0.58) | HPGDALDH1A1KDM4EMAPTPPARG | |
| SCHEMBL11553318 | 0.72 | MAPT (0.75) | SMN1; SMN2HPGDHSD17B10TP53NPC1 | |
| SCHEMBL13067553 | 0.72 | NPC1 (0.63) | SMN1; SMN2HPGDHSD17B10TP53NPC1 | |
| SCHEMBL11520960 | 0.71 | MAPT (0.52) | SMN1; SMN2HPGDHSD17B10TP53NPC1 | |
| SCHEMBL11327576 | 0.71 | MAPT (0.57) | SMN1; SMN2HPGDHSD17B10TP53NPC1 | |
| SCHEMBL10849435 | 0.71 | NPC1 (0.69) | SMN1; SMN2HPGDHSD17B10TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265804-A | BENZOXAZOYLBENZOATES, OXADIAZOLE-2,5-DIBENZOATES, BENZOTRIAZOLES AND BENZOTRIAZOTRIAZOLES | EASTMAN KODAK COMPANY (US) | 1981-05-05 | — | — | US | claimed |
| US-4265804-A | BENZOXAZOYLBENZOATES, OXADIAZOLE-2,5-DIBENZOATES, BENZOTRIAZOLES AND BENZOTRIAZOTRIAZOLES | EASTMAN KODAK COMPANY (US) | 1981-05-05 | — | — | US | disclosed |