Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231021 | 0.91 | LMNA (0.47) | LMNAALDH1A1ACHEVDRMEN1 | |
| SCHEMBL4414443 | 0.86 | MTOR (0.52) | LMNATSHRMTORRAB9AGRM7 | |
| Hydrochloric Acid SCHEMBL10786964 | 0.84 | CYP3A4 (0.54) | LMNAALDH1A1TSHRMTORRAB9A | |
| SCHEMBL14302911 | 0.81 | ACHE (0.54) | LMNAALDH1A1TSHRACHESMN1; SMN2 | |
| SCHEMBL29266047 | 0.80 | LMNA (0.56) | LMNAALDH1A1TSHRALOX12ACHE | |
| SCHEMBL13184555 | 0.80 | LMNA (0.56) | LMNAALDH1A1TSHRALOX12ACHE | |
| Hydrochloric Acid SCHEMBL29091952 | 0.78 | LMNA (0.55) | LMNAALDH1A1TSHRALOX12ACHE | |
| Acetic Acid SCHEMBL18138499 | 0.78 | LMNA (0.50) | LMNAALDH1A1TSHRHPGDMTOR | |
| SCHEMBL13164341 | 0.77 | LMNA (0.53) | LMNAALDH1A1TSHRALOX12ACHE | |
| SCHEMBL5512077 | 0.77 | VDR (0.58) | LMNAALDH1A1SMN1; SMN2HPGDVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551042-B | Preparation method of aromatic azo organic compound | 云南民族大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-110551042-A | preparation method of aromatic azo organic compound | UNIV YUNNAN MINZU | 2019-12-10 | — | — | CN | disclosed |
| US-9932390-B2 | Compositions comprising the NC2 domain of collagen IX and methods of using same | SHRINERS HOSPITAL FOR CHILDREN (US) | 2018-04-03 | — | — | US | disclosed |
| US-20160222089-A1 | COMPOSITIONS COMPRISING THE NC2 DOMAIN OF COLLAGEN IX AND METHODS OF USING SAME | SHRINERS HOSPITAL FOR CHILDREN (US) | 2016-08-04 | — | — | US | disclosed |
| US-9315561-B2 | Compositions comprising the NC2 domain of collagen IX and methods of using same | SHRINERS HOSPITAL FOR CHILDREN (US) | 2016-04-19 | — | — | US | disclosed |
| WO-2014014310-A1 | A NOVEL COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2014-01-23 | — | — | WO | disclosed |
| US-20130157257-A1 | Compositions Comprising the NC2 Domain of Collagen IX and Methods of Using Same | SHRINERS HOSPITAL FOR CHILDREN (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2011150073-A2 | COMPOSITIONS COMPRISING THE NC2 DOMAIN OF COLLAGEN IX AND METHODS OF USING SAME | SHRINERS HOSPITALS FOR CHILDREN (US) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157257-A1 | Compositions Comprising the NC2 Domain of Collagen IX and Methods of Using Same | COL14A1, COL2A1, COLGALT1 | LMNA 2709/4885ALDH1A1 4754/4885TSHR 3167/4885 |
| US-20160222089-A1 | COMPOSITIONS COMPRISING THE NC2 DOMAIN OF COLLAGEN IX AND METHODS OF USING SAME | COL14A1, COL2A1, COLGALT1 | LMNA 2709/4885ALDH1A1 4754/4885TSHR 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.