SCHEMBL4579225

SCHEMBL4579225

COc1ccc2cc(O)c(C(=O)NCCCN3CCOCC3)cc2c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
KDM4E B2RXH2 4/20 0.60
GAA P10253 3/20 0.60
ALDH1A1 P00352 3/20 0.60
HSD17B10 Q99714 3/20 0.60
HPGD P15428 2/20 0.60
MEN1 O00255 1/20 0.60
CYP1A2 P05177 1/20 0.60
GLA P06280 1/20 0.60
CYP3A4 P08684 1/20 0.60
KMT2A Q03164 1/20 0.60
TDP1 Q9NUW8 1/20 0.57
POLB P06746 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
MAPT P10636 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2D6 P10635 1/20 0.56
ALOX15 P16050 1/20 0.56
CYP2C19 P33261 1/20 0.54
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11341388 0.89 KDM4E (0.54) LMNAKDM4EGAAALDH1A1HSD17B10
SCHEMBL4580300 0.86 ALDH1A1 (0.69) LMNAKDM4EGAAALDH1A1HSD17B10
SCHEMBL11238408 0.85 LMNA (0.69) LMNAKDM4EALDH1A1HSD17B10HPGD
Hydrochloric Acid SCHEMBL10348659 0.85 ALDH1A1 (0.68) LMNAKDM4EGAAALDH1A1HSD17B10
SCHEMBL10336968 0.82 KDM4E (0.64) LMNAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL11330614 0.80 MAPT (0.55) KDM4EALDH1A1HSD17B10HPGDGLA
SCHEMBL10379079 0.79 CYP2C9 (0.73) KDM4EGAAALDH1A1TDP1POLB
SCHEMBL8356152 0.79 CYP1A2 (0.68) LMNAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL11338593 0.79 TSHR (0.59) LMNAHPGDCYP1A2GLAKMT2A
SCHEMBL11338560 0.79 CYP2C19 (0.61) LMNAALDH1A1MEN1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207110-A 2,5-DIALKOXY-4-MORPHOLINO-BENZENE DIAZONIUM SALT AND COUPLER COMBINATION TO GIVE BLACK IMAGE HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-10 US claimed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-20050187102-A1 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-08-25 US disclosed
US-6723482-B2 COMPRISES DIAZO COUPLERS; SUPPRESSES DISCOLORATION OVER TIME WITHOUT DECREASING LIGHT RESISTANCE OF COLOR DEVELOPED PORTION; PRESERVABILITY FUJI PHOTO FILM CO., LTD. (JP) 2004-04-20 US disclosed
US-20030022092-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-01-30 US disclosed
US-5935757-A HIGH COLOR DEVELOPING SENSITIVITY AND EXCELLENT STORABILITY. USING AN ESTER- OR AMIDE CONTAINING SULFOAMIDOBENZENE IN A LAYER CONTAINING A DIAZONIUM SALT AND A REACTIVE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1999-08-10 US disclosed
US-4590143-A STORAGE STABILITY, QUICK DEVELOPMENT, COUPLER, ACID STABILIZER COMPONENTS HOECHST AKTIENGESELLSCHAFT (DE) 1986-05-20 US disclosed
US-4492749-A PHOTOSTABILITY HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-08 US disclosed
US-4334004-A Light-sensitive diazotype material with 2-hydroxy-3-naphthoic acid amides having 6-sulfonic acid amide substitution HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-08 US disclosed
US-4321373-A 2-Hydroxy-3-naphthoic acid amides HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-23 US disclosed
US-4207110-A 2,5-DIALKOXY-4-MORPHOLINO-BENZENE DIAZONIUM SALT AND COUPLER COMBINATION TO GIVE BLACK IMAGE HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-10 US disclosed