Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28131361 | 0.80 | TTR (0.40) | CA1CA2CA4CA7PHLPP2 | |
| SCHEMBL10869750 | 0.79 | ALDH1A1 (0.33) | ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL28130645 | 0.77 | TTR (0.47) | CA1CA2CA4CA7 | |
| SCHEMBL27639016 | 0.77 | RAPGEF4 (0.42) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL11141120 | 0.77 | CA1 (0.33) | CA1CA2CA4CA7ALDH1A1 | |
| SCHEMBL5776430 | 0.76 | RAPGEF4 (0.41) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| Potassium SCHEMBL5776437 | 0.76 | RAPGEF4 (0.41) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL11581606 | 0.72 | ALDH1A1 (0.33) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL10951252 | 0.72 | RAB9A (0.43) | ALDH1A1TDP1 | |
| SCHEMBL27573806 | 0.72 | CA12 (0.37) | CA1CA2CA7ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254025-A | Disazo and polyazo dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-03 | — | — | US | disclosed |