Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | RECQL | P46063 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27639016 | 0.98 | RAPGEF4 (0.42) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 | |
| SCHEMBL5776430 | 0.97 | RAPGEF4 (0.41) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 | |
| SCHEMBL29289294 | 0.90 | PRKCI (0.37) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 | |
| Potassium Ion SCHEMBL5776435 | 0.84 | TDP1 (0.37) | TDP1ALDH1A1RECQLL3MBTL1KDM4E | |
| SCHEMBL10612152 | 0.80 | ALDH1A1 (0.46) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 | |
| SCHEMBL11628912 | 0.80 | ALDH1A1 (0.42) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 | |
| SCHEMBL28603286 | 0.79 | ALDH1A1 (0.45) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 | |
| Lithium SCHEMBL29868510 | 0.79 | ALDH1A1 (0.45) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL11761732 | 0.79 | ALDH1A1 (0.45) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 | |
| SCHEMBL27484633 | 0.79 | ALDH1A1 (0.45) | RAPGEF4TDP1ALDH1A1RECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142588-A1 | Acetoacetylation of alcohols, thiols and amines in a microreactor | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142588-A1 | Acetoacetylation of alcohols, thiols and amines in a microreactor | ADH1A, GRHPR, AKR1C2 | RAPGEF4 3043/4885TDP1 4248/4885ALDH1A1 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.