Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 10/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063901 | 1.00 | CTRB1 (0.54) | CTRB1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19345761 | 0.96 | CTRB1 (0.53) | CTRB1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19386326 | 0.89 | CTRB1 (0.57) | CTRB1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL6647414 | 0.89 | CTRB1 (0.51) | CTRB1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL9574175 | 0.88 | CASP1 (0.60) | CTRB1CASP1ITGB3ITGA2BHTT | |
| SCHEMBL7136060 | 0.86 | CTRB1 (0.66) | CTRB1CASP1HTT | |
| SCHEMBL19295561 | 0.86 | SYK (0.57) | CTRB1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL6652290 | 0.86 | HTT (0.63) | CTRB1CASP1HTT | |
| SCHEMBL6649610 | 0.86 | HTT (0.63) | CTRB1CASP1HTT | |
| SCHEMBL17816593 | 0.86 | CTSL (0.55) | CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035337-A1 | 3-O-Demethyl derivatives of sannamycin C and antibiotic AX-127B-1 | ABBOTT LABORATORIES (US) | 1981-09-09 | — | — | EP | disclosed |
| US-4283529-A | 3-O-Demethyl derivatives of Sannamycin C and antibiotic AX-127B-1 | ABBOTT LABORATORIES (US) | 1981-08-11 | — | — | US | disclosed |