SCHEMBL9574175

SCHEMBL9574175

O=C(O)C[C@@H](CCCc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 12/20 0.60
CTRB1 P17538 2/20 0.56
ITGB3 P05106 1/20 0.48
ITGA2B P08514 1/20 0.48
HTT P42858 1/20 0.48
SYK P43405 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5702489 0.93 CASP1 (0.54) CASP1CTRB1ITGB3ITGA2B
SCHEMBL11340396 0.88 CTRB1 (0.54) CASP1CTRB1ITGB3ITGA2BHTT
SCHEMBL7063901 0.88 CTRB1 (0.54) CASP1CTRB1ITGB3ITGA2BHTT
SCHEMBL9574079 0.88 CASP1 (0.54) CASP1ITGB3ITGA2B
SCHEMBL7136060 0.87 CTRB1 (0.66) CASP1CTRB1HTTSYK
SCHEMBL17816593 0.87 CTSL (0.55) CTRB1SYK
SCHEMBL6649610 0.87 HTT (0.63) CASP1CTRB1HTT
SCHEMBL19345761 0.87 CTRB1 (0.53) CASP1CTRB1ITGB3ITGA2B
SCHEMBL6652290 0.87 HTT (0.63) CASP1CTRB1HTT
SCHEMBL25302472 0.86 CTRB1 (0.58) CASP1CTRB1ITGB3ITGA2BSYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561758-A2 Method of preparing optically active homo-beta-amino acids MONSANTO COMPANY (US) 1993-09-22 EP disclosed