SCHEMBL1134080

SCHEMBL1134080

O=[Sb]([O-])([O-])F.O=[Sb]([O-])([O-])F.O=[Sb]([O-])([O-])F.O=[Sb]([O-])([O-])F.O=[Sb]([O-])([O-])F.O=[Sb]([O-])([O-])F.c1ccc([I+]c2ccccc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7081560 1.00 LMNA (0.30) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL9685437 1.00 LMNA (0.30) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL447938 0.90 LMNA (0.32) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL31314887 0.90 MAPT (0.32) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL17417803 0.84
SCHEMBL6306790 0.83 CA4 (0.43) TP53MAPT
SCHEMBL4854404 0.83 CA4 (0.43) TP53MAPT
SCHEMBL36560 0.78 ALDH1A1 (0.40) LMNACYP1A2CYP3A4
Toliodium SCHEMBL10780090 0.76 TLR9 (0.37) LMNACYP3A4MAPT
SCHEMBL30561568 0.75 CYP3A4 (0.35) LMNATP53CYP1A2CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285339-B1 INITIATOR SYSTEM CONTAINING A DIARYLAKYLAMINE DERIVATIVE, HARDENABLE COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2012-12-19 EP disclosed
US-8314162-B2 Initiator system containing a diarylalkylamine derivate, hardenable composition and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-11-20 US disclosed
US-20110077361-A1 INITIATOR SYSTEM CONTAINING A DIARYLALKYLAMINE DERIVATE, HARDENABLE COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2011-03-31 US disclosed
EP-2285339-A1 INITIATOR SYSTEM CONTAINING A DIARYLAKYLAMINE DERIVATIVE, HARDENABLE COMPOSITION AND USE THEREOF 3M Innovative Properties Company (US) 2011-02-23 EP disclosed
WO-2009151957-A1 INITIATOR SYSTEM CONTAINING A DIARYLAKYLAMINE DERIVATIVE, HARDENABLE COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-17 WO disclosed
EP-2133064-A1 Initiator system containing a diarylalkylamine derivate, hardenable composition and use thereof 3M Innovative Properties Company (US) 2009-12-16 EP disclosed