Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270152 | 0.91 | TSHR (0.42) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL11267480 | 0.84 | TSHR (0.54) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL11634111 | 0.81 | NPC1 (0.37) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL11269321 | 0.76 | MAPT (0.61) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL11631103 | 0.76 | HSD17B10 (0.32) | ALDH1A1MAPTNPC1RAB9ATLR8 | |
| SCHEMBL11269464 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL7497548 | 0.72 | L3MBTL1 (0.51) | SOAT1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL7171613 | 0.72 | NPC1 (0.70) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL7500928 | 0.72 | L3MBTL1 (0.51) | SOAT1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL14802124 | 0.72 | LTA4H (0.53) | SOAT1ALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251527-A | ANTIINFLAMMATORY AGENTS | DIAMOND SHAMROCK CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |