Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.42 |
| ▸ | ESR1 | P03372 | 11/20 | 0.42 |
| ▸ | ENTPD5 | O75356 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184205 | 0.79 | AKT1 (0.56) | AKT1ESR2ESR1ENTPD5CETP | |
| SCHEMBL30513267 | 0.79 | AKT1 (0.56) | AKT1ESR2ESR1ENTPD5CETP | |
| SCHEMBL11705856 | 0.78 | AKT1 (0.55) | AKT1ESR2ESR1ENTPD5CETP | |
| SCHEMBL4475359 | 0.76 | AKT1 (0.49) | AKT1ESR2ESR1ENTPD5CETP | |
| SCHEMBL7787622 | 0.75 | AKT1 (0.51) | AKT1ESR2ESR1ENTPD5CETP | |
| SCHEMBL11346965 | 0.74 | ALOX15 (0.37) | MAPT | |
| SCHEMBL9749407 | 0.74 | AKT1 (0.51) | AKT1ESR2ESR1ENTPD5CETP | |
| SCHEMBL13005003 | 0.74 | AKT1 (0.48) | AKT1 | |
| SCHEMBL8653315 | 0.73 | AKT1 (0.50) | AKT1PTPN1 | |
| SCHEMBL2348744 | 0.72 | AKT1 (0.46) | AKT1ESR2ESR1ENTPD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015562-B1 | PROCESS FOR PREPARING CHROMAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1981-11-18 | — | — | EP | disclosed |
| US-4268446-A | REACTING A HYDROQUINONE, LEWIS ACID OR BASE DERIVATIVE AND A NITRILE IN THE PRESENCE OF AN INERT SOLVENT | BASF AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| EP-0015562-A1 | Process for preparing chroman derivatives | BASF Aktiengesellschaft (DE) | 1980-09-17 | — | — | EP | disclosed |