SCHEMBL7787622

SCHEMBL7787622

Oc1ccc2c(c1)CCC1(CCc3cc(O)ccc3O1)O2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.51
RXRA P19793 1/20 0.47
ESR1 P03372 6/20 0.44
ESR2 Q92731 6/20 0.44
CYP3A4 P08684 1/20 0.39
ENTPD5 O75356 2/20 0.39
CETP P11597 1/20 0.37
MAPT P10636 3/20 0.37
GAA P10253 2/20 0.37
MEN1 O00255 1/20 0.37
MITF O75030 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PTPN1 P18031 1/20 0.36
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21346943 0.92 AKT1 (0.46) AKT1RXRAESR1ESR2CYP3A4
SCHEMBL11705856 0.84 AKT1 (0.55) AKT1RXRAESR1ESR2CYP3A4
SCHEMBL4475359 0.81 AKT1 (0.49) AKT1ESR1ESR2CYP3A4ENTPD5
SCHEMBL30513267 0.81 AKT1 (0.56) AKT1ESR1ESR2ENTPD5CETP
SCHEMBL3184205 0.81 AKT1 (0.56) AKT1ESR1ESR2ENTPD5CETP
SCHEMBL2348744 0.78 AKT1 (0.46) AKT1ESR1ESR2ENTPD5GAA
SCHEMBL13005003 0.76 AKT1 (0.48) AKT1DRD2DRD4
SCHEMBL9749407 0.76 AKT1 (0.51) AKT1RXRAESR1ESR2ENTPD5
SCHEMBL11405269 0.75 AKT1 (0.44) AKT1RXRAESR1ESR2ENTPD5
SCHEMBL8653315 0.75 AKT1 (0.50) AKT1RXRACYP3A4GAAPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0886179-B1 Silver halide light-sensitive color photographic material KONISHIROKU PHOTO IND (JP) 2001-10-24 EP disclosed
EP-0601836-B1 Silver halide light sensitive color photographic material KONISHIROKU PHOTO IND (JP) 2000-10-04 EP disclosed
US-6010809-A CONTAINING COUPLER AND THERMOTROPIC LIQUID CRYSTAL KONICA CORPORATION (JP) 2000-01-04 US disclosed
EP-0886179-A1 Silver halide light-sensitive color photographic material KONICA CORPORATION (JP) 1998-12-23 EP disclosed
US-5376520-A Containing polyvalent alcohol; lightfast color images KONICA CORPORATION (JP) 1994-12-27 US disclosed
EP-0601836-A2 Silver halide light sensitive color photographic material KONICA CORPORATION (JP) 1994-06-15 EP disclosed
EP-0286850-B1 METHOD FOR PREVENTING AN ORGANIC COLORED SUBSTANCE FROM FADING BY LIGHT, STABILIZED COLORED COMPOSITIONS AND PHOTOGRAPHIC ELEMENTS AND MATERIALS KONICA CORPORATION (JP) 1993-05-19 EP disclosed
EP-0286850-A1 Method for preventing an organic colored substance from fading by light, stabilized colored compositions and photographic elements and materials KONICA CORPORATION (JP) 1988-10-19 EP disclosed