Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938292 | 0.84 | KCNMA1 (0.53) | KCNMA1SLC9A1NR1H2NR1H3TSHR | |
| SCHEMBL30049983 | 0.84 | KCNMA1 (0.53) | KCNMA1SLC9A1NR1H2NR1H3TSHR | |
| SCHEMBL5207084 | 0.82 | RXRA (0.44) | KCNMA1RXRAKDM4E | |
| SCHEMBL11025009 | 0.80 | SLC9A1 (0.52) | KCNMA1SLC9A1NR1H2NR1H3TSHR | |
| SCHEMBL7762346 | 0.79 | KDM4E (0.49) | KMT2AKCNMA1KDM4ENPC1L3MBTL1 | |
| SCHEMBL4639410 | 0.79 | SLC9A1 (0.54) | KCNMA1SLC9A1NR1H2NR1H3 | |
| SCHEMBL7645987 | 0.77 | KCNMA1 (0.43) | KCNMA1RXRAKDM4ENPC1L3MBTL1 | |
| SCHEMBL18599169 | 0.76 | KCNMA1 (0.55) | KCNMA1SLC9A1TSHRSMN1; SMN2 | |
| SCHEMBL6064913 | 0.74 | KCNMA1 (0.67) | KMT2AMEN1KCNMA1SLC9A1KDM4E | |
| SCHEMBL5416738 | 0.73 | KCNMA1 (0.54) | KCNMA1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251435-A | FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
| US-4239891-A | BY REACTING A 4-HYDROXY-4-CYANOPIPERIDINE WITH A TERTIARY ALCOHOL OR AN OLEFIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |