SCHEMBL6064913

SCHEMBL6064913

Oc1ccccc1-n1nnc2cc(Cl)ccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KCNMA1 Q12791 8/20 0.67
▸ KDM4E B2RXH2 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ CHEK1 O14757 1/20 0.41
▸ LIMK1 P53667 1/20 0.41
▸ MAPK14 Q16539 1/20 0.41
▸ CLK4 Q9HAZ1 1/20 0.41
▸ HPGD P15428 1/20 0.40
▸ GLA P06280 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ FGFR1 P11362 1/20 0.38
▸ TDP2 O95551 1/20 0.38
▸ GAA P10253 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ SLC9A1 P19634 1/20 0.37
▸ F12 P00748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7645987 0.82 KCNMA1 (0.43) KCNMA1KDM4ENPC1L3MBTL1CHEK1
SCHEMBL502853 0.82 KCNMA1 (0.67) KCNMA1NPC1GLATHRBGAA
SCHEMBL80393 0.80 KCNMA1 (1.00) KCNMA1HPGDGAAMEN1MAPT
SCHEMBL11343969 0.74 ADORA3 (0.39) KCNMA1KDM4ENPC1L3MBTL1CHEK1
SCHEMBL28980715 0.73 HPGD (0.61) KCNMA1KDM4ENPC1L3MBTL1CHEK1
SCHEMBL6067857 0.72 CHEK1 (0.39) KCNMA1KDM4ENPC1L3MBTL1CHEK1
SCHEMBL7762346 0.72 KDM4E (0.49) KCNMA1KDM4ENPC1L3MBTL1HPGD
SCHEMBL29193530 0.72 KCNMA1 (0.42) KCNMA1KDM4ENPC1L3MBTL1CHEK1
SCHEMBL3177701 0.72 KCNMA1 (0.40) KCNMA1NPC1L3MBTL1CHEK1LIMK1
SCHEMBL5183293 0.71 KCNMA1 (0.59) KCNMA1GAAKMT2AMGAMAMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305098-A1 USE OF AT LEAST ONE SULFUR-CONTAINING AMINO ACID FOR STABILIZING RECYCLED THERMOPLASTICS, STABILIZED RECYCLED THERMOPLASTIC, STABILIZER COMPOSITION, MASTERBATCH, AND MOLDING COMPOUND OR MOLDED PART Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-01-17 — — EP disclosed
CN-103080203-B Stabilized photoactive composition and use thereof ENI SPA 2015-07-22 — — CN disclosed
CN-102093282-B Oxime ester photoinitiators CIBA SC HOLDING AG 2014-02-12 — — CN disclosed
CN-103080203-A Stabilized photoactive composition and use thereof ENI SPA 2013-05-01 — — CN disclosed
CN-101273083-A Method for improving the flowability of polymer melts CIBA HOLDING INC (CH) 2008-09-24 — — CN disclosed
EP-1692221-A1 WEATHERFAST PIGMENTED POLYSTYRENE Ciba Specialty Chemicals Holding Inc. (CH) 2006-08-23 — — EP disclosed
CN-1235984-C Fluorinated-photoinitiators in dual cure resins CIBA SC HOLDING AG (CH) 2006-01-11 — — CN disclosed
CN-1222565-C Stabilizer mixtures CIBA SC HOLDING AG (CH) 2005-10-12 — — CN disclosed
CN-1214035-C Surface-active photoinitiators CIBA SC HOLDING AG (CH) 2005-08-10 — — CN disclosed
WO-2005054353-A1 WEATHERFAST PIGMENTED POLYSTYRENE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-06-16 — — WO disclosed
CN-1474862-A Fluorinated-photoinitiators in dual cure resins �������⻯ѧƷ�ع����޹�˾ 2004-02-11 — — CN disclosed
CN-1447814-A Surface-active photoinitiators CIBA SC HOLDING AG (CH) 2003-10-08 — — CN disclosed
CN-1432042-A Stabilizer mixtures CIBA SC HOLDING AG (CH) 2003-07-23 — — CN disclosed
CN-1079808-C Synergic stabilizer mixture CIBA SC HOLDING AG (CH) 2002-02-27 — — CN disclosed
EP-0782597-A1 STABILIZED RECYCLED PLASTICS Ciba SC Holding AG (CH) 1997-07-09 — — EP disclosed
CN-1141931-A Synergic stabilizer mixture CIBA GEIGY AG (CH) 1997-02-05 — — CN disclosed
WO-1996009341-A1 STABILIZED RECYCLED PLASTICS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-03-28 — — WO disclosed
US-4415684-A POLYMER STABILIZERS THE B. F. GOODRICH COMPANY (US) 1983-11-15 — — US disclosed
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