Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690126 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAALDH1A1FFAR1MEN1 | |
| SCHEMBL2622341 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAALDH1A1FFAR1SCN9A | |
| SCHEMBL10691845 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAALDH1A1FFAR1SCN9A | |
| SCHEMBL11549227 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAALDH1A1FFAR1SCN9A | |
| SCHEMBL11349350 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAALDH1A1FFAR1SCN9A | |
| SCHEMBL731273 | 0.81 | L3MBTL1 (0.62) | SMN1; SMN2LMNAALDH1A1FFAR1MEN1 | |
| Haloxyfop SCHEMBL3675562 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAALDH1A1FFAR1MEN1 | |
| SCHEMBL9363159 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAALDH1A1FFAR1MEN1 | |
| Haloxyfop SCHEMBL33627 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAALDH1A1FFAR1MEN1 | |
| SCHEMBL9449585 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAALDH1A1FFAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000483-B1 | TRIFLUOROMETHYL PYRIDINYL(OXY/THIO)PHENOXY PROPANOIC ACIDS AND PROPANOLS AND DERIVATIVES THEREOF | THE DOW CHEMICAL COMPANY (US) | 1981-10-14 | — | — | EP | disclosed |
| EP-0000483-A1 | Trifluoromethyl pyridinyl(oxy/thio)phenoxy propanoic acids and propanols and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1979-02-07 | — | — | EP | disclosed |