Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 7/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349350 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL6901995 | 0.87 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL10690126 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL11344508 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL10584608 | 0.85 | FFAR1 (0.68) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL10839309 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL11360493 | 0.84 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL2622337 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL20626585 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL9519820 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1LMNAFFAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158677-B2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-04-17 | — | — | US | disclosed |
| US-20090239830-A1 | Treatment of viral infections by modulation of host cell metabolic pathways | KADMON CORPORATION, LLC | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239830-A1 | Treatment of viral infections by modulation of host cell metabolic pathways | GOT2, MAVS, ME3 | SMN1; SMN2 2585/4885ALDH1A1 1469/4885LMNA 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.