Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450387 | 0.84 | EPHX1 (0.44) | TRPM8TRPA1ALDH1A1EPHX1CYP19A1 | |
| SCHEMBL4594644 | 0.84 | EPHX1 (0.44) | TRPM8TRPA1ALDH1A1EPHX1CYP19A1 | |
| SCHEMBL4251270 | 0.81 | TRPM8 (0.46) | TRPM8TRPA1ALDH1A1EPHX1LMNA | |
| SCHEMBL4593967 | 0.80 | EPHX1 (0.41) | TRPM8TRPA1ALDH1A1EPHX1LMNA | |
| SCHEMBL1983430 | 0.79 | TRPM8 (0.52) | TRPM8TRPA1ALDH1A1EPHX1LMNA | |
| SCHEMBL114683 | 0.79 | EPHX1 (0.46) | TRPM8TRPA1ALDH1A1EPHX1LMNA | |
| SCHEMBL8066155 | 0.78 | TRPM8 (0.50) | TRPM8TRPA1ALDH1A1EPHX1LMNA | |
| SCHEMBL7750544 | 0.78 | TRPM8 (0.55) | TRPM8TRPA1ALDH1A1EPHX1LMNA | |
| SCHEMBL2761888 | 0.78 | TRPM8 (0.50) | TRPM8TRPA1ALDH1A1EPHX1LMNA | |
| SCHEMBL113450 | 0.78 | TRPM8 (0.55) | TRPM8TRPA1ALDH1A1EPHX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 932 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3690134-B1 | LIQUID-STATE TEMPORARY REINFORCING MATERIAL, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | UNIV SHANGHAI (CN) | 2024-10-16 | — | — | EP | claimed |
| CN-116583261-A | Method for combating microorganisms using menthol derivatives | 西姆莱斯股份公司 | 2023-08-11 | — | — | CN | claimed |
| EP-3081207-B1 | USE OF A LIPOSOME COMPOSITION | SYMRISE AG (DE) | 2022-09-21 | — | — | EP | claimed |
| CN-114502138-A | Improvements in or relating to organic compounds | 奇华顿股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| EP-3687311-A1 | AMIDES FOR GENERATING A TRIGEMINAL EFFECT | Symrise AG (DE) | 2020-08-05 | — | — | EP | claimed |
| EP-3142499-B1 | HOMOVANILLIC ACID ESTERS, IN PARTICULAR FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS | SYMRISE AG (DE) | 2019-10-30 | — | — | EP | claimed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | claimed |
| WO-2019063069-A1 | AMIDES FOR GENERATING A TRIGEMINAL EFFECT | SYMRISE AG (DE) | 2019-04-04 | — | — | WO | claimed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | claimed |
| EP-2785309-B1 | COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT | HENKEL AG & CO KGAA (DE) | 2017-07-12 | — | — | EP | claimed |
| EP-1698331-B1 | Use of a volatile rhinological effective composition on fibrous tissues to provide a sensation of sinusoidal relieve | PROCTER & GAMBLE (US) | 2009-04-08 | — | — | EP | claimed |
| EP-2014273-A1 | Use of methyl methyl ether and another ether to provide a feeling of cleanliness and purity | Symrise GmbH & Co. KG (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-1341512-B1 | RHINOLOGICAL AGENTS | SYMRISE GMBH & CO KG (DE) | 2008-12-31 | — | — | EP | claimed |
| EP-2008530-A1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | Symrise GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | claimed |
| EP-1888012-A2 | OIL-CONTAINING DEODORIZING AEROSOL COMPOSITIONS HAVING SKIN-COOLING ACTIVE SUBSTANCES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-02-20 | — | — | EP | claimed |
| WO-2006128622-A2 | OIL-CONTAINING DEODORIZING AEROSOL COMPOSITIONS HAVING SKIN-COOLING ACTIVE SUBSTANCES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-12-07 | — | — | WO | claimed |
| EP-1466949-A1 | Non-toxic coating composition, methods of use thereof and articles protected from attachment of biofouling organisms | Symrise GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | claimed |
| EP-1430880-A2 | Alcohol free deodorant spray containing skin cooling active agents | Hans Schwarzkopf & Henkel GmbH & Co. KG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1341512-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002041861-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2002-05-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099342-A1 | COOLING PRODUCT | TRPA1, TRPV2, NISCH | TRPM8 44/4885TRPA1 1/4885ALDH1A1 40/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | TRPM8 1/4885TRPA1 8/4885ALDH1A1 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.