Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264414 | 0.83 | KMO (0.35) | — | |
| SCHEMBL11263659 | 0.79 | KMO (0.38) | — | |
| SCHEMBL9414548 | 0.74 | LMNA (0.32) | — | |
| SCHEMBL3043661 | 0.74 | HSD17B10 (0.31) | — | |
| SCHEMBL11260590 | 0.71 | CDC25B (0.32) | — | |
| SCHEMBL16754865 | 0.70 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1742128 | 0.70 | KMO (0.35) | — | |
| SCHEMBL374759 | 0.69 | ALDH1A1 (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6225051 | 0.68 | ENPP1 (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6825208 | 0.68 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023033-A1 | 2.4.6-Trihalo-5-halocarbonyl-pyrimidines and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | disclosed |