SCHEMBL9414548

SCHEMBL9414548

O=C(Cl)Oc1c(Cl)nc(Cl)nc1Cl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10585533 0.81 LMNA (0.32) LMNAALDH1A1ALOX15TSHR
SCHEMBL9414553 0.79 KEAP1 (0.31) LMNAALDH1A1ALOX15TSHR
SCHEMBL11343033 0.79 LMNA (0.35) LMNAALDH1A1ALOX15TSHR
SCHEMBL10782244 0.76 CYP1A2 (0.44)
SCHEMBL11345258 0.74 PDE4A (0.30)
SCHEMBL9513161 0.69 CA1 (0.35)
SCHEMBL27996882 0.69 ABCB11 (0.33) LMNAALDH1A1TSHR
SCHEMBL9414543 0.69 KEAP1 (0.32)
SCHEMBL7087131 0.69 NFKB1 (0.37) ALDH1A1
SCHEMBL4082477 0.67 ALDH1A1 (0.39) LMNAALDH1A1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0603595-A1 Fibre reactive dyes, method for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-29 EP disclosed
EP-0321784-B1 FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS BAYER AG (DE) 1992-03-18 EP disclosed
EP-0255890-B1 PROCESS FOR THE REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS BAYER AG (DE) 1990-08-29 EP disclosed
EP-0151792-B1 REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS BAYER AG (DE) 1988-11-30 EP disclosed
EP-0114575-B1 2,4-DIAMINO-6-HALOGEN-5-TRIFLUOROMETHYL PYRIMIDINE WITH HERBICIDAL ACTIVITY CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed
EP-0158882-B1 TRIPHENEDIOXAZINE DYES BAYER AG (DE) 1987-12-16 EP disclosed
EP-0076410-B1 REACTIVE ANTHRAQUINONE DYES BAYER AG (DE) 1987-04-08 EP disclosed
EP-0097289-B1 AZO DYESTUFFS BAYER AG (DE) 1986-10-15 EP disclosed
EP-0108924-B1 HEAVY METAL-CONTAINING FORMAZANE DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE IN THE DYEING AND PRINTING OF FIBRE MATERIALS BAYER AG (DE) 1986-07-02 EP disclosed
EP-0103218-B1 10-PHENYL-1,3,9-TRIAZAANTHRACENES AND PHOTOPOLYMERISABLE MIXTURE CONTAINING THESE COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1986-04-30 EP disclosed
EP-0043411-A2 Reactive disazo dyestuffs, process for their preparation and their use in dyeing and printing materials containing nitrogen and/or hydroxyle groups BAYER AG (DE) 1982-01-13 EP disclosed
EP-0001451-B1 WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP disclosed
EP-0001629-B1 WATER-SOLUBLE, FIBRE-REACTIVE, GREEN AZO-PHTHALOCYANINE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-08-12 EP disclosed
EP-0023033-A1 2.4.6-Trihalo-5-halocarbonyl-pyrimidines and process for preparing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-28 EP disclosed
EP-0021372-A2 Copper complexes of disazo reactive dyestuffs BAYER AG (DE) 1981-01-07 EP disclosed
EP-0013936-A1 Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups BAYER AG (DE) 1980-08-06 EP disclosed
EP-0013378-A1 Process for the production of reserve effects on polyester-cellulose blended textile materials CASSELLA Aktiengesellschaft (DE) 1980-07-23 EP disclosed
EP-0001614-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their application, as well as the phthalocyanine pyrazolone intermediates and their preparation CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
EP-0001629-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
EP-0001451-A1 Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-04-18 EP disclosed