Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947196 | 0.74 | KDM4E (0.45) | LMNAPOLBPKMMAPTKDM4E | |
| SCHEMBL3123708 | 0.65 | CPB2 (0.44) | LMNAMAPTFAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL28673893 | 0.65 | CA1 (0.50) | LMNAFAAHMGLLKMT2AALDH1A1 | |
| SCHEMBL23833841 | 0.64 | TSHR (0.52) | LMNAMAPTFAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL3122846 | 0.64 | CPB2 (0.46) | LMNAMAPTFAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL28532812 | 0.64 | CPB2 (0.45) | LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6778466 | 0.63 | MEN1 (0.53) | LMNAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3124113 | 0.63 | CPB2 (0.47) | LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3125182 | 0.63 | CPB2 (0.47) | LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8946980 | 0.62 | HTR2C (0.43) | LMNAPOLBPKMMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |