Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.63 |
| ▸ | CTSS | P25774 | 7/20 | 0.63 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614151 | 0.96 | CTSK (0.60) | CTSKCTSSRENITGB3ITGA2B | |
| SCHEMBL9876535 | 0.91 | CTSK (0.63) | CTSKCTSSRENCTSLCTSB | |
| SCHEMBL22962442 | 0.91 | CTSK (0.63) | CTSKCTSSRENCTSLCTSB | |
| SCHEMBL9876540 | 0.91 | CTSK (0.63) | CTSKCTSSRENCTSLCTSB | |
| SCHEMBL30645691 | 0.90 | CTSS (0.62) | CTSKCTSSRENITGB3ITGA2B | |
| SCHEMBL11346677 | 0.90 | CTSK (0.59) | CTSKCTSSRENCTSLCTSB | |
| SCHEMBL28630396 | 0.90 | CTSS (0.72) | CTSKCTSSRENITGB3ITGA2B | |
| SCHEMBL30645671 | 0.89 | CTSS (0.61) | CTSKCTSSRENITGB3ITGA2B | |
| SCHEMBL31181957 | 0.89 | CTSS (0.61) | CTSKCTSSRENITGB3ITGA2B | |
| SCHEMBL11125595 | 0.89 | CTSK (0.63) | CTSKCTSSRENCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273704-A | N-Adamantane-substituted tetrapeptide amides | G. D. SEARLE & CO. (US) | 1981-06-16 | — | — | US | disclosed |