Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.49 |
| ▸ | CCKBR | P32239 | 5/20 | 0.49 |
| ▸ | CCKAR | P32238 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345784 | 0.96 | CTSK (0.63) | CTSKCTSSITGB3ITGA2BACE | |
| SCHEMBL8145513 | 0.90 | CTSK (0.56) | CTSKCTSSRENOPRD1CCKBR | |
| SCHEMBL28630396 | 0.90 | CTSS (0.72) | CTSKCTSSITGB3ITGA2BACE | |
| SCHEMBL31383409 | 0.89 | CTSS (0.58) | CTSKCTSSITGB3ITGA2BACE | |
| SCHEMBL30772338 | 0.89 | CTSS (0.58) | CTSKCTSSITGB3ITGA2BACE | |
| SCHEMBL11125595 | 0.89 | CTSK (0.63) | CTSKCTSSRENOPRD1CCKBR | |
| SCHEMBL28799360 | 0.89 | CTSS (0.60) | CTSKCTSSITGB3ITGA2BACE | |
| SCHEMBL28799353 | 0.89 | CTSS (0.60) | CTSKCTSSITGB3ITGA2BACE | |
| SCHEMBL11346677 | 0.88 | CTSK (0.59) | CTSKCTSSRENOPRD1CCKBR | |
| SCHEMBL231980 | 0.87 | CTSS (0.71) | CTSKCTSSITGB3ITGA2BACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |