Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11272284 | 0.98 | CASP3 (0.56) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL11407006 | 0.98 | CASP3 (0.59) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL9829900 | 0.91 | FAAH (0.59) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL24766317 | 0.86 | P4HB (0.62) | CASP3FAAHMGLLCASP7 | |
| SCHEMBL17948289 | 0.86 | P4HB (0.62) | CASP3FAAHMGLLCASP7 | |
| SCHEMBL11278746 | 0.85 | CASP3 (0.74) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL11640205 | 0.83 | CASP3 (0.67) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL11631975 | 0.83 | CASP3 (0.56) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL11458909 | 0.79 | CASP3 (0.58) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL24836229 | 0.79 | FAAH (0.76) | CASP3FAAHMGLLKAT2AKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001503-B1 | ANTITHROMBOTIC COMPOSITIONS CONTAINING BENZISOTHIAZOLONES | BEECHAM GROUP PLC (GB) | 1981-01-07 | — | — | EP | claimed |
| EP-0001503-A1 | Antithrombotic compositions containing benzisothiazolones | BEECHAM GROUP PLC (GB) | 1979-04-18 | — | — | EP | claimed |
| EP-0001503-B1 | ANTITHROMBOTIC COMPOSITIONS CONTAINING BENZISOTHIAZOLONES | BEECHAM GROUP PLC (GB) | 1981-01-07 | — | — | EP | disclosed |
| US-4186203-A | ANTITHROMBOTIC ACTIVITY | BEECHAM GROUP LIMITED (GB) | 1980-01-29 | — | — | US | disclosed |
| EP-0001503-A1 | Antithrombotic compositions containing benzisothiazolones | BEECHAM GROUP PLC (GB) | 1979-04-18 | — | — | EP | disclosed |