Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 7/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25287000 | 0.98 | PNMT (0.42) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL3050301 | 0.82 | DRD2 (0.50) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL11362964 | 0.80 | HTR2C (0.44) | HTR2AHTR2CHTR2BADRA1AFYN | |
| SCHEMBL11358755 | 0.80 | ADRA1A (0.34) | ADRA1AFYNDRD2DRD3CA12 | |
| SCHEMBL24095373 | 0.80 | ADRA1A (0.38) | HTR2AHTR2CHTR2BADRA1AFYN | |
| SCHEMBL11359509 | 0.80 | ADRA1A (0.34) | ADRA1AFYNDRD2DRD3CA12 | |
| SCHEMBL11349526 | 0.80 | DRD2 (0.40) | HTR2AHTR2CHTR2BADRA1AFYN | |
| SCHEMBL11352780 | 0.80 | HTR2A (0.44) | HTR2AHTR2CHTR2BADRA1AFYN | |
| Hydrochloric Acid SCHEMBL25243090 | 0.79 | ADRA1A (0.37) | HTR2AHTR2CHTR2BADRA1AFYN | |
| Hydrochloric Acid SCHEMBL30748037 | 0.79 | DRD2 (0.39) | HTR2AHTR2CHTR2BADRA1AFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001002-B1 | INDANAMINES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-08-12 | — | — | EP | claimed |
| EP-0001002-A1 | Indanamines, processes for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-03-07 | — | — | EP | claimed |
| US-20230174516-A1 | AMINO-PYRIMIDINE AMIDES | HOFFMANN-LA ROCHE INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174516-A1 | AMINO-PYRIMIDINE AMIDES | HOFFMANN-LA ROCHE INC. (US) | 2023-06-08 | — | — | US | disclosed |
| WO-2021249908-A2 | AMINO-PYRIMIDINE AMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |
| EP-0001002-B1 | INDANAMINES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-08-12 | — | — | EP | disclosed |
| EP-0001002-A1 | Indanamines, processes for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-03-07 | — | — | EP | disclosed |
| US-4128666-A | PHENYLETHANOLAMINE N-METHYL-TRANSFERASE INHIBITORS | SMITHKLINE CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174516-A1 | AMINO-PYRIMIDINE AMIDES | TYMS, TYMP, DPYD | HTR2A 1739/4885HTR2C 1803/4885HTR2B 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.