Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042925 | 0.89 | MEN1 (0.63) | SHBGMEN1MAPTKMT2ACNR2 | |
| SCHEMBL14767383 | 0.85 | SHBG (0.58) | SHBGMEN1MAPTKMT2ACNR2 | |
| SCHEMBL2721684 | 0.82 | MEN1 (0.56) | SHBGMEN1MAPTKMT2ACNR2 | |
| SCHEMBL28696476 | 0.82 | ALDH1A1 (0.60) | SHBGMEN1MAPTKMT2ACNR2 | |
| SCHEMBL11359638 | 0.79 | TP53 (0.50) | SHBGMEN1MAPTKMT2ACNR2 | |
| SCHEMBL13948417 | 0.79 | CNR2 (0.48) | SHBGMEN1MAPTKMT2ACNR2 | |
| SCHEMBL30402144 | 0.78 | L3MBTL1 (0.45) | SHBGMAPTKMT2AHTTALDH1A1 | |
| SCHEMBL943719 | 0.78 | L3MBTL1 (0.45) | SHBGMAPTKMT2AHTTALDH1A1 | |
| SCHEMBL159113 | 0.77 | ALDH1A1 (0.56) | SHBGMEN1MAPTKMT2AHPGD | |
| SCHEMBL5402022 | 0.77 | HPGD (0.51) | SHBGMEN1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002097-B1 | TRIPHENYLALKENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-05 | — | — | EP | disclosed |