Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.51 |
| ▸ | BCHE | P06276 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336420 | 0.82 | CYP1A2 (0.45) | DRD2KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11334553 | 0.81 | CYP1A2 (0.43) | DRD2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11336089 | 0.80 | MT-CO2 (0.41) | ACHEBCHEMEN1KMT2AMAOB | |
| SCHEMBL11334573 | 0.79 | CYP1A2 (0.49) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11338664 | 0.79 | IKBKE (0.48) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11329934 | 0.74 | CYP1A2 (0.51) | ACHEBCHEKMT2ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11337723 | 0.73 | CYP1A2 (0.50) | ACHEBCHEKMT2ACYP1A2CYP3A4 | |
| SCHEMBL1002852 | 0.71 | MEN1 (0.81) | ACHEDRD2MEN1KMT2ADRD4 | |
| SCHEMBL27324146 | 0.69 | DRD2 (0.58) | ACHEBCHEDRD2MEN1KMT2A | |
| SCHEMBL22642807 | 0.69 | DRD2 (0.58) | ACHEBCHEDRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259338-A | Benzofuranyl-tetrahydropyridines and -piperidines, their acid addition salts and antidepressant preparations thereof | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |