Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135154 | 0.84 | TDP1 (0.32) | CYP11B2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6179156 | 0.81 | CYP4F2 (0.34) | CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL1135178 | 0.72 | LMNA (0.35) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1135133 | 0.71 | TDP1 (0.33) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1135128 | 0.70 | — | — | |
| SCHEMBL4940831 | 0.69 | SSTR4 (0.40) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL2499613 | 0.68 | ACACB (0.34) | — | |
| SCHEMBL9685381 | 0.68 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25746311 | 0.67 | VRK1 (0.32) | CYP11B2KDM4EALDH1A1 | |
| SCHEMBL25305890 | 0.67 | POLB (0.47) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958946-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-02-23 | — | — | EP | disclosed |