Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12810186 | 1.00 | TP53 (0.43) | TP53ALDH1A1RAB9AMITFL3MBTL1 | |
| SCHEMBL13002954 | 0.88 | NPC1 (0.52) | TP53ALDH1A1RAB9AKMT2AVNN1 | |
| SCHEMBL13002948 | 0.88 | LMNA (0.57) | ALDH1A1RAB9AL3MBTL1HDAC6HDAC8 | |
| SCHEMBL1135097 | 0.88 | NPC1 (0.52) | TP53ALDH1A1RAB9AKMT2AVNN1 | |
| SCHEMBL12810187 | 0.83 | POLB (0.48) | TP53ALDH1A1RAB9AL3MBTL1KMT2A | |
| SCHEMBL13002947 | 0.82 | POLB (0.49) | ALDH1A1RAB9AKMT2ANPC1MAPK1 | |
| SCHEMBL13002957 | 0.80 | LMNA (0.54) | TP53ALDH1A1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL13002960 | 0.80 | CTDSP1 (0.43) | ALDH1A1RAB9AL3MBTL1KMT2ATSHR | |
| SCHEMBL1135207 | 0.80 | CTDSP1 (0.43) | ALDH1A1RAB9AL3MBTL1KMT2ATSHR | |
| SCHEMBL1008409 | 0.74 | ALDH1A1 (0.46) | TP53ALDH1A1RAB9AL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436115-B2 | Catalyst systems based on carbonylamino fulvenes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-05-07 | — | — | US | disclosed |
| EP-2167517-B1 | CATALYSTS SYSTEMS BASED ON CARBONYLAMINO FULVENES | TOTAL PETROCHEMICALS RES FELUY (BE) | 2011-02-23 | — | — | EP | disclosed |
| US-20100311931-A1 | Catalyst Systems Based on Carbonylamino Fulvenes | TOTAL PETROCHEMICALS RESEARCH FELUY | 2010-12-09 | — | — | US | disclosed |
| EP-2167517-A2 | CATALYSTS SYSTEMS BASED ON CARBONYLAMINO FULVENES | Total Petrochemicals Research Feluy (BE) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009013196-A2 | CATALYSTS SYSTEMS BASED ON CARBONYLAMINO FULVENES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-29 | — | — | WO | disclosed |
| EP-2019110-A1 | Catalysts systems based on carbonylamino fulvenes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311931-A1 | Catalyst Systems Based on Carbonylamino Fulvenes | CYCS, FOS, COPE | TP53 3146/4885ALDH1A1 1863/4885RAB9A 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.