SCHEMBL1135191

SCHEMBL1135191

C=C(C(=O)O)C(CC)(CC)CN

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6449919 0.85 TET2 (0.34) TET2
SCHEMBL450544 0.84 MEN1 (0.32)
SCHEMBL1135149 0.82 TDP1 (0.36)
SCHEMBL2199441 0.79 ODC1 (0.36) KDM4E
SCHEMBL4618155 0.75 MEN1 (0.38) KDM4E
SCHEMBL2994453 0.75 GRIK1 (0.31) TET2
SCHEMBL6576734 0.74 FDPS (0.39)
SCHEMBL6446033 0.74 FDPS (0.36)
SCHEMBL2991692 0.72
SCHEMBL6448587 0.72 FDPS (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2519692-B1 PROCESS TO ENHANCING DRY STRENGTH OF PAPER BY TREATMENT WITH VINYLAMINE-CONTAINING POLYMERS AND ACRYLAMIDE CONTAINING POLYMERS SOLENIS TECHNOLOGIES CAYMAN LP (CH) 2017-03-15 EP claimed
US-8673988-B2 Graft copolymers for ion exchange chromatography MERCK PATENT GMBH (DE) 2014-03-18 US claimed
US-8636875-B2 Enhanced dry strength and drainage performance by combining glyoxalated acrylamide-containing polymers with cationic aqueous dispersion polymers HERCULES INCORPORATED (US) 2014-01-28 US claimed
WO-2006110540-A2 ANTIMICROBIAL POLYMER COATINGS AND A METHOD PRODUCING THEM VIA CHEMICAL VAPOUR DEPOSITION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-10-19 WO claimed
US-20060228966-A1 Chemical vapor deposition of antimicrobial polymer coatings MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-10-12 US claimed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
EP-2310104-B1 MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-10-18 EP disclosed
EP-2285485-B1 CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS MERCK PATENT GMBH (DE) 2014-04-23 EP disclosed
US-8673988-B2 Graft copolymers for ion exchange chromatography MERCK PATENT GMBH (DE) 2014-03-18 US disclosed
US-20120295992-A1 Ce(IV)-INITIATED GRAFT POLYMERISATION ON POLYMERS CONTAINING NO HYDROXYL GROUPS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2012-11-22 US disclosed
US-20110136925-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-06-09 US disclosed
EP-2310104-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY Merck Patent GmbH (DE) 2011-04-20 EP disclosed
EP-2285485-A1 CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS Merck Patent GmbH (DE) 2011-02-23 EP disclosed
US-20100303877-A1 Controlled Release Hydrogel Films BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-12-02 US disclosed
EP-2153877-A1 Mixed graft polymers for ion exchange chromatography MERCK PATENT GmbH (DE) 2010-02-17 EP disclosed
WO-2010012358-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2010-02-04 WO disclosed
WO-2009143953-A1 CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS MERCK PATENT GMBH (DE) 2009-12-03 WO disclosed
US-7563734-B2 Chemical vapor deposition of antimicrobial polymer coatings MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-07-21 US disclosed
WO-2006110540-A2 ANTIMICROBIAL POLYMER COATINGS AND A METHOD PRODUCING THEM VIA CHEMICAL VAPOUR DEPOSITION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-10-19 WO disclosed
US-20060228966-A1 Chemical vapor deposition of antimicrobial polymer coatings MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120295992-A1 Ce(IV)-INITIATED GRAFT POLYMERISATION ON POLYMERS CONTAINING NO HYDROXYL GROUPS CCR4, CES2, HLA-C KDM4E 873/4885TET2 1050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.