SCHEMBL1135149

SCHEMBL1135149

C=C(C(N)=O)C(CC)(CC)CN

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28117043 0.84 TDP1 (0.35) TDP1
SCHEMBL1135191 0.82 KDM4E (0.32)
SCHEMBL21016285 0.76 TDP1 (0.39) TDP1
SCHEMBL6234395 0.75 ALOX15 (0.38)
SCHEMBL28218207 0.75 FDPS (0.41)
SCHEMBL1562569 0.71 TDP1 (0.39) TDP1
SCHEMBL3229799 0.71 TDP1 (0.39) TDP1
SCHEMBL1135166 0.71 TDP1 (0.39) TDP1
SCHEMBL528103 0.70 TDP1 (0.36) TDP1
SCHEMBL4618155 0.70 MEN1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10166527-B2 Surface modification of porous base supports MERCK PATENT GMBH (DE) 2019-01-01 US claimed
EP-2310104-B1 MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-10-18 EP claimed
US-20150298097-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2015-10-22 US claimed
EP-2914377-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS Merck Patent GmbH (DE) 2015-09-09 EP claimed
WO-2014067605-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2014-05-08 WO claimed
US-8673988-B2 Graft copolymers for ion exchange chromatography MERCK PATENT GMBH (DE) 2014-03-18 US claimed
JP-2011529508-A 2011-12-08 JP claimed
US-20110136925-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-06-09 US claimed
EP-2310104-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY Merck Patent GmbH (DE) 2011-04-20 EP claimed
EP-2153877-A1 Mixed graft polymers for ion exchange chromatography MERCK PATENT GmbH (DE) 2010-02-17 EP claimed
WO-2010012358-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2010-02-04 WO claimed
US-20220098233-A1 Mixed Bed Ion Exchange Adsorber EMD MILLIPORE CORP (US) 2022-03-31 US disclosed
US-11236125-B2 Mixed bed ion exchange adsorber EMD MILLIPORE CORPORATION (US) 2022-02-01 US disclosed
US-10166527-B2 Surface modification of porous base supports MERCK PATENT GMBH (DE) 2019-01-01 US disclosed
US-20170298091-A1 Mixed Bed Ion Exchange Adsorber EMD MILLIPORE CORPORATION 2017-10-19 US disclosed
US-20110073547-A1 Ce(IV)-initiated graft polymerisation on polymers containing no hydroxyl groups MERCK PATENT GESELLSCHAFT (DE) 2011-03-31 US disclosed
EP-2285485-A1 CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS Merck Patent GmbH (DE) 2011-02-23 EP disclosed
EP-2153877-A1 Mixed graft polymers for ion exchange chromatography MERCK PATENT GmbH (DE) 2010-02-17 EP disclosed
WO-2010012358-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2010-02-04 WO disclosed
WO-2009143953-A1 CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS MERCK PATENT GMBH (DE) 2009-12-03 WO disclosed