Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353518 | 0.86 | LMNA (0.51) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL9569322 | 0.83 | TP53 (0.73) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11358397 | 0.83 | RAB9A (0.55) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11363818 | 0.83 | MAPT (0.43) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11367839 | 0.83 | LMNA (0.43) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11367847 | 0.83 | RAB9A (0.57) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11358489 | 0.82 | LMNA (0.44) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11364113 | 0.81 | F2RL3 (0.47) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11366406 | 0.80 | F2RL3 (0.44) | MAPTTP53RAB9ALMNASMN1; SMN2 | |
| SCHEMBL10803806 | 0.79 | TP53 (0.70) | MAPTTP53RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244952-A | Imidazo[2',1':2,3]-thiazolo[5,4-c]pyridines and composition thereof for treating immune diseases | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |