Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358397 | 0.83 | RAB9A (0.55) | MAPTTP53LMNASMN1; SMN2TSHR | |
| SCHEMBL11353518 | 0.83 | LMNA (0.51) | F2RL3MAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL11367839 | 0.83 | LMNA (0.43) | MAPTTP53LMNASMN1; SMN2TSHR | |
| SCHEMBL11363818 | 0.83 | MAPT (0.43) | F2RL3MAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL31338670 | 0.83 | MET (0.52) | F2RL3MAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL11367847 | 0.83 | RAB9A (0.57) | MAPTTP53LMNASMN1; SMN2TSHR | |
| SCHEMBL11351985 | 0.80 | MAPT (0.61) | MAPTTP53LMNASMN1; SMN2TSHR | |
| SCHEMBL11358489 | 0.80 | LMNA (0.44) | MAPTTP53LMNASMN1; SMN2TSHR | |
| SCHEMBL31338679 | 0.79 | LMNA (0.53) | F2RL3MAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL11366925 | 0.78 | F2RL3 (0.46) | F2RL3MAPTTP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244952-A | Imidazo[2',1':2,3]-thiazolo[5,4-c]pyridines and composition thereof for treating immune diseases | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |