Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306312 | 0.86 | POLB (0.56) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL718296 | 0.83 | PPARA (0.67) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL9624674 | 0.82 | ALDH1A1 (0.52) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL7322651 | 0.82 | PPARA (0.72) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL9443129 | 0.81 | POLB (0.59) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL717957 | 0.80 | LMNA (0.63) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL402778 | 0.80 | ALDH1A1 (0.57) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL8972732 | 0.80 | POLB (0.58) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL8971785 | 0.79 | ALDH1A1 (0.59) | POLBAPEX1RECQLHPGDALDH1A1 | |
| SCHEMBL9443153 | 0.79 | HPGD (0.59) | POLBAPEX1RECQLHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275065-A | USEFUL FOR SKIN GRAFTS AND ORGAN TRANSPLANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-23 | — | — | US | disclosed |