SCHEMBL9306312

SCHEMBL9306312

O=C(O)C(Sc1nc2ccccc2s1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.56
APEX1 P27695 1/20 0.56
RECQL P46063 1/20 0.56
ALDH1A1 P00352 5/20 0.56
HPGD P15428 5/20 0.56
HSD17B10 Q99714 3/20 0.56
CYP1A2 P05177 3/20 0.56
ALOX15 P16050 2/20 0.56
CYP2C19 P33261 2/20 0.56
HIF1A Q16665 2/20 0.56
MAPK1 P28482 2/20 0.56
CYP2C9 P11712 1/20 0.56
TSHR P16473 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ADRA2A P08913 1/20 0.56
FBP1 P09467 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
DRD2 P14416 1/20 0.56
ADRA2B P18089 1/20 0.56
ADRA2C P18825 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11352115 0.86 POLB (0.55) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL718296 0.84 PPARA (0.67) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL7322651 0.83 PPARA (0.72) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL9443129 0.82 POLB (0.59) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL9304684 0.82 POLB (0.53) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL8972732 0.81 POLB (0.58) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL402778 0.81 ALDH1A1 (0.57) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL717957 0.81 LMNA (0.63) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL8971785 0.80 ALDH1A1 (0.59) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL9443153 0.80 HPGD (0.59) POLBAPEX1RECQLALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10669429-B2 Ambient cure compositions for making coatings having humidity and corrosion resistance and methods of use DOW GLOBAL TECHNOLOGIES LLC (US) 2020-06-02 US disclosed
US-20180371259-A1 AMBIENT CURE COMPOSITIONS FOR MAKING COATINGS HAVING HUMIDITY AND CORROSION RESISTANCE AND METHODS OF USE ROHM AND HAAS COMPANY 2018-12-27 US disclosed
US-10131813-B2 Ambient cure compositions for making coatings having humidity and corrosion resistance and methods of use DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-20 US disclosed
EP-3121235-B1 AMBIENT CURE COMPOSITIONS FOR MAKING COATINGS HAVING HUMIDITY AND CORROSION RESISTANCE AND METHODS OF USE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-28 EP disclosed
US-20180022956-A1 AMBIENT CURE COMPOSITIONS FOR MAKING COATINGS HAVING HUMIDITY AND CORROSION RESISTANCE AND METHODS OF USE DOW GLOBAL TECHNOLOGIES LLC 2018-01-25 US disclosed
EP-3121235-A1 AMBIENT CURE COMPOSITIONS FOR MAKING COATINGS HAVING HUMIDITY AND CORROSION RESISTANCE AND METHODS OF USE Dow Global Technologies LLC (US) 2017-01-25 EP disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
EP-0375614-B1 CORROSION-INHIBITING COATING COMPOSITIONS CIBA-GEIGY AG (CH) 1993-03-31 EP disclosed
US-5198482-A Benzothiazole carboxylic acid amine salt CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
EP-0129506-B1 HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS CIBA-GEIGY AG (CH) 1991-03-06 EP disclosed
EP-0375614-A1 Corrosion-inhibiting coating compositions CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed
EP-0129506-A2 Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids CIBA-GEIGY AG (CH) 1984-12-27 EP disclosed