Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614326 | 1.00 | MTNR1A (0.53) | MTNR1AMTNR1BLMNAMEN1KMT2A | |
| SCHEMBL6548206 | 0.89 | MAPT (0.47) | MTNR1AMTNR1BMEN1KMT2ACES2 | |
| SCHEMBL20534163 | 0.89 | ESR1 (0.61) | MTNR1AMTNR1BKMT2ACES2CES1 | |
| SCHEMBL20534166 | 0.89 | ESR1 (0.61) | MTNR1AMTNR1BKMT2ACES2CES1 | |
| SCHEMBL560984 | 0.89 | LMNA (0.51) | MTNR1AMTNR1BLMNAMEN1KMT2A | |
| SCHEMBL7052945 | 0.87 | LMNA (0.58) | MTNR1AMTNR1BLMNAMEN1KMT2A | |
| SCHEMBL11352148 | 0.85 | TDP1 (0.59) | MTNR1AMTNR1BLMNACES2CES1 | |
| SCHEMBL5606420 | 0.83 | ESR1 (0.62) | MTNR1AMTNR1BMEN1KMT2ACYP19A1 | |
| SCHEMBL7912475 | 0.83 | ESR1 (0.62) | MTNR1AMTNR1BMEN1KMT2ACYP19A1 | |
| SCHEMBL1226484 | 0.83 | ESR1 (0.62) | MTNR1AMTNR1BMEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288235-B1 | Agents for the improvement of the vulcanisation behaviour in the preparation of grafted or crosslinked polymers and filled resins | EVONIK DEGUSSA GMBH (DE) | 2008-02-20 | — | — | EP | claimed |
| US-6864323-B2 | Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics | DEGUSSA AG (DE) | 2005-03-08 | — | — | US | claimed |
| US-20030114604-A1 | Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics | DEGUSA AG (DE) | 2003-06-19 | — | — | US | claimed |
| US-6864323-B2 | Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics | DEGUSSA AG (DE) | 2005-03-08 | — | — | US | disclosed |
| US-20030114604-A1 | Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics | DEGUSA AG (DE) | 2003-06-19 | — | — | US | disclosed |