SCHEMBL23865484

SCHEMBL23865484

Cc1cc(F)c(-c2c(F)cc(C)c(F)c2F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32
NOTUM Q6P988 1/20 0.31
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17772466 0.90 RAPGEF4 (0.32) RAPGEF4NOTUMPTGS2
SCHEMBL23865418 0.88
SCHEMBL17779399 0.88 PTGS2 (0.39) ACHEPTGS2
SCHEMBL17254525 0.86 ALDH1A1 (0.37)
SCHEMBL9320683 0.84 PTGS2 (0.39) ACHEPTGS2
SCHEMBL5363306 0.82
SCHEMBL5351777 0.82
SCHEMBL823681 0.79 RAPGEF4 (0.38) ACHERAPGEF4
SCHEMBL30567470 0.79 RAPGEF4 (0.38) ACHERAPGEF4
SCHEMBL5357403 0.78 PAX8 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3886194-A2 FLUORINATED AROMATIC SMALL MOLECULES AS FUNCTIONAL ADDITIVES FOR DISPERSION OF CONDUCTIVE POLYMERS Heraeus Deutschland GmbH & Co KG (DE) 2021-09-29 EP disclosed