Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351414 | 0.86 | TAAR1 (0.50) | TSHRTAAR1CYP3A4 | |
| SCHEMBL11349209 | 0.82 | KDM4E (0.37) | TSHRHSD17B10L3MBTL1MAPTNPSR1 | |
| SCHEMBL11365947 | 0.82 | L3MBTL1 (0.36) | TSHRHSD17B10L3MBTL1MAPTNPSR1 | |
| SCHEMBL11357222 | 0.74 | ALOX15 (0.41) | HSD17B10L3MBTL1MAPTNPSR1LMNA | |
| SCHEMBL23326296 | 0.73 | LMNA (0.52) | TSHRHSD17B10L3MBTL1MAPTNPSR1 | |
| SCHEMBL21757374 | 0.73 | LMNA (0.47) | TSHRHSD17B10L3MBTL1MAPTNPSR1 | |
| SCHEMBL29775469 | 0.73 | LMNA (0.52) | TSHRHSD17B10L3MBTL1MAPTNPSR1 | |
| SCHEMBL11355764 | 0.72 | THRB (0.35) | TSHRHSD17B10L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL6394052 | 0.72 | LMNA (0.39) | TSHRHSD17B10L3MBTL1MAPTNPSR1 | |
| SCHEMBL12797854 | 0.69 | MAPT (0.47) | TSHRHSD17B10L3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |