Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11356052 | 0.74 | ATM (0.37) | EPHX1SIGMAR1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3418772 | 0.69 | SIGMAR1 (0.50) | SIGMAR1MEN1KMT2ATDP1HSD17B10 | |
| SCHEMBL11355662 | 0.68 | MEN1 (0.51) | EPHX1MEN1KMT2AGAAMAPT | |
| SCHEMBL11355667 | 0.68 | MEN1 (0.51) | EPHX1MEN1KMT2AGAAMAPT | |
| SCHEMBL11356919 | 0.66 | PLAU (0.51) | SIGMAR1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL11361810 | 0.65 | SMN1; SMN2 (0.43) | SIGMAR1SMN1; SMN2GAAMAPTRAB9A | |
| SCHEMBL11883551 | 0.64 | HTR3E (0.57) | SIGMAR1TDP1HSD17B10ALDH1A1TP53 | |
| SCHEMBL27899476 | 0.63 | MAPT (0.41) | EPHX1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL11358962 | 0.62 | NOS3 (0.40) | SIGMAR1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL2388970 | 0.62 | EPHX1 (0.70) | EPHX1SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4290971-A | HYPOTENSIVE AGENTS | DSO "PHARMACHIM" (BG) | 1981-09-22 | — | — | US | claimed |
| US-4290971-A | HYPOTENSIVE AGENTS | DSO "PHARMACHIM" (BG) | 1981-09-22 | — | — | US | disclosed |