Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280556 | 0.83 | TSHR (0.57) | TP53ALOX15MCL1SMN1; SMN2TSHR | |
| SCHEMBL11504215 | 0.81 | ALDH1A1 (0.49) | TP53ALOX15MCL1HPGDALDH1A1 | |
| SCHEMBL4389091 | 0.79 | BRD4 (0.53) | TP53ALOX15MAPT | |
| SCHEMBL5452089 | 0.79 | HPGD (0.53) | SMN1; SMN2HPGDALDH1A1MAPTNPC1 | |
| SCHEMBL15048513 | 0.78 | L3MBTL1 (0.53) | TP53ALOX15MCL1ALDH1A1TSHR | |
| SCHEMBL3731595 | 0.77 | L3MBTL1 (0.67) | TP53ALOX15MCL1SMN1; SMN2HPGD | |
| SCHEMBL4028646 | 0.76 | TP53 (0.50) | TP53ALOX15ALDH1A1MAPTTSHR | |
| SCHEMBL7375365 | 0.76 | MCL1 (0.46) | TP53ALOX15MCL1SMN1; SMN2HPGD | |
| SCHEMBL12749081 | 0.75 | TP53 (0.63) | TP53ALOX15ALDH1A1MAPTTSHR | |
| SCHEMBL11531093 | 0.75 | MCL1 (0.60) | TP53MCL1SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001721-B1 | N-CYANO- AND N-ALKYNYL-2-(SUBSTITUTED PHENOXY)BUTYRAMIDES AND THE USE THEREOF AS MILDEWICIDES | STAUFFER CHEMICAL COMPANY (US) | 1981-09-16 | — | — | EP | disclosed |