SCHEMBL11356019

SCHEMBL11356019

CCCc1cc(C(=O)c2ccccc2)ccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
PPARG P37231 2/20 0.51
PPARA Q07869 1/20 0.51
RXRA P19793 1/20 0.49
POLB P06746 2/20 0.48
CDC25A P30304 1/20 0.47
CDC25B P30305 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
SRD5A2 P31213 1/20 0.47
LTB4R Q15722 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
ALDH1A1 P00352 3/20 0.45
HPGD P15428 1/20 0.45
AKR1C3 P42330 1/20 0.44
RAB9A P51151 1/20 0.44
ELANE P08246 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11352786 0.91 KDM4E (0.51) KDM4EPPARGPPARARXRAPOLB
SCHEMBL11351394 0.88 LTB4R (0.54) KDM4EPPARGPPARALTB4R
SCHEMBL11358915 0.88 LTB4R (0.54) KDM4EPPARGPPARALTB4R
SCHEMBL80902 0.87 RXRA (0.52) KDM4EPPARGPPARARXRATDP1
SCHEMBL3840599 0.85 RXRA (0.51) KDM4EPPARGPPARARXRATDP1
SCHEMBL11352213 0.84 KDM4E (0.54) KDM4EPOLBCDC25ACDC25BHSD17B10
SCHEMBL11350944 0.84 KDM4E (0.48) KDM4EPPARGPPARAPOLBCDC25A
SCHEMBL11352798 0.84 HTR6 (0.50) KDM4EPOLBCDC25ACDC25BHSD17B10
SCHEMBL6933360 0.83 PPARG (0.52) PPARGPPARATDP1L3MBTL1ATM
SCHEMBL11357115 0.81 KDM4E (0.48) KDM4EPOLBCDC25ACDC25BHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0000705-B1 USE OF ESTERS OR AMIDES OF BENZOYLBENZOIC ACIDS AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE COMPOSITION CONTAINING THEM STAUFFER CHEMICAL COMPANY (US) 1981-02-11 EP disclosed
EP-0000705-A1 Use of esters or amides of benzoylbenzoic acids as photoinitiators and photopolymerisable composition containing them STAUFFER CHEMICAL COMPANY (US) 1979-02-21 EP disclosed
US-4080275-A POLYMERIZATION INITIATOR, ETHYLENICALLY UNSATURATED MONOMER STAUFFER CHEMICAL COMPANY (US) 1978-03-21 US disclosed