Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828870 | 0.98 | HCAR3 (0.39) | HCAR3ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL11363553 | 0.87 | CMA1 (0.34) | HCAR3 | |
| SCHEMBL11349865 | 0.85 | CMA1 (0.35) | HCAR3MAPT | |
| SCHEMBL11364413 | 0.83 | GPR84 (0.37) | HCAR3MAPT | |
| SCHEMBL11353511 | 0.83 | CA2 (0.36) | HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL11358820 | 0.82 | GPR84 (0.39) | HCAR3MAPT | |
| SCHEMBL18839845 | 0.79 | HCAR3 (0.40) | HCAR3ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL829122 | 0.75 | ALDH1A1 (0.41) | HCAR3ALDH1A1KDM4EHPGDHCAR2 | |
| SCHEMBL20518729 | 0.73 | HCAR3 (0.36) | HCAR3ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL1647137 | 0.69 | KCNN4 (0.42) | HCAR3ALDH1A1SMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297489-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1981-10-27 | — | — | US | disclosed |