Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351553 | 0.87 | L3MBTL1 (0.64) | HDAC8L3MBTL1ALDH1A1NR1H4NOTUM | |
| SCHEMBL11174792 | 0.78 | MAPT (0.44) | HDAC8L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL11174901 | 0.77 | L3MBTL1 (0.48) | HDAC8L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL11161665 | 0.77 | NOTUM (0.54) | HDAC8L3MBTL1ALDH1A1NR1H4NOTUM | |
| SCHEMBL11152712 | 0.72 | NOTUM (0.49) | HDAC8L3MBTL1ALDH1A1NR1H4NOTUM | |
| SCHEMBL21776935 | 0.72 | NOTUM (0.70) | L3MBTL1ALDH1A1NR1H4NOTUMNPC1 | |
| SCHEMBL91656 | 0.71 | SMN1; SMN2 (0.70) | L3MBTL1ALDH1A1NR1H4NOTUMNPC1 | |
| SCHEMBL2810636 | 0.71 | NR1H4 (1.00) | L3MBTL1ALDH1A1NR1H4NPC1RAB9A | |
| SCHEMBL4865565 | 0.71 | NOTUM (1.00) | HDAC8L3MBTL1ALDH1A1NR1H4NOTUM | |
| SCHEMBL7254229 | 0.71 | NOTUM (0.68) | HDAC8L3MBTL1ALDH1A1NR1H4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |