Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344812 | 0.84 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11174792 | 0.82 | MAPT (0.44) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11353069 | 0.78 | MAPT (0.47) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11357489 | 0.77 | HDAC8 (0.56) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10197292 | 0.75 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11156637 | 0.73 | MAPT (0.41) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11180901 | 0.70 | MEN1 (0.40) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11152963 | 0.70 | POLB (0.46) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11351553 | 0.70 | L3MBTL1 (0.64) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13535715 | 0.69 | DRD2 (0.41) | MEN1KMT2ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007529-B1 | ANTIPROTOZOAL OXADIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-07-20 | — | — | EP | claimed |
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | claimed |
| EP-0007529-A1 | Antiprotozoal oxadiazole derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-02-06 | — | — | EP | claimed |
| EP-0007529-B1 | ANTIPROTOZOAL OXADIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-07-20 | — | — | EP | disclosed |
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| EP-0007529-A1 | Antiprotozoal oxadiazole derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |