Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341223 | 0.90 | EPHX2 (0.47) | NNMTEPHX2MAPK1L3MBTL1IDO1 | |
| SCHEMBL11351151 | 0.87 | NNMT (0.43) | NNMTEPHX2HCAR3MAPK1L3MBTL1 | |
| SCHEMBL11364407 | 0.86 | NNMT (0.49) | NNMTEPHX2HCAR3HDAC1 | |
| SCHEMBL11364463 | 0.86 | NNMT (0.49) | NNMTEPHX2HCAR3HDAC1 | |
| SCHEMBL5040612 | 0.78 | LNPEP (0.51) | EPHX2ALDH1A1LMNAHCAR3MAPK1 | |
| SCHEMBL3466195 | 0.76 | NNMT (0.63) | NNMTEPHX2ALDH1A1LMNAHCAR3 | |
| SCHEMBL838587 | 0.71 | RAB9A (0.51) | L3MBTL1 | |
| SCHEMBL3465475 | 0.71 | NNMT (0.69) | NNMTEPHX2HCAR3 | |
| SCHEMBL19151094 | 0.70 | NNMT (0.63) | NNMTEPHX2HCAR3MAPK1 | |
| SCHEMBL19116338 | 0.70 | NNMT (0.58) | NNMTEPHX2HCAR3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10568913-B2 | Method for generating mature β-like cells | HEALTHREGEN PTY LTD (AU) | 2020-02-25 | — | — | US | disclosed |
| US-20160045554-A1 | METHOD FOR GENERATING MATURE BETA-LIKE CELLS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2016-02-18 | — | — | US | disclosed |
| WO-2014153620-A1 | METHOD FOR GENERATING MATURE β-LIKE CELLS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2014-10-02 | — | — | WO | disclosed |
| US-4258052-A | APPLYING TOPICALLY | YU RUEY J | 1981-03-24 | — | — | US | disclosed |