Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364463 | 1.00 | NNMT (0.49) | NNMTEPHX2LTA4HS1PR1S1PR3 | |
| SCHEMBL11359159 | 0.86 | NNMT (0.49) | NNMTEPHX2HCAR3HDAC1 | |
| SCHEMBL11341223 | 0.83 | EPHX2 (0.47) | NNMTEPHX2TSHR | |
| SCHEMBL11351151 | 0.81 | NNMT (0.43) | NNMTEPHX2S1PR1S1PR3HCAR3 | |
| SCHEMBL3466195 | 0.76 | NNMT (0.63) | NNMTEPHX2HCAR3SMN1; SMN2HDAC1 | |
| SCHEMBL5040612 | 0.73 | LNPEP (0.51) | EPHX2TSHRHCAR3 | |
| SCHEMBL11316730 | 0.72 | NNMT (0.62) | NNMTEPHX2HCAR3SMN1; SMN2 | |
| SCHEMBL11038421 | 0.72 | LTA4H (0.60) | LTA4HS1PR1S1PR3 | |
| SCHEMBL7902676 | 0.72 | LTA4H (0.60) | LTA4HS1PR1S1PR3 | |
| SCHEMBL3465475 | 0.70 | NNMT (0.69) | NNMTEPHX2HCAR3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524774-B1 | Topical two step polytherapy for treatment of psoriasis and other skin disorders | CYMBIOTICS, INC. (US) | 2013-09-03 | — | — | US | claimed |
| US-10568913-B2 | Method for generating mature β-like cells | HEALTHREGEN PTY LTD (AU) | 2020-02-25 | — | — | US | disclosed |
| US-20160045554-A1 | METHOD FOR GENERATING MATURE BETA-LIKE CELLS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2016-02-18 | — | — | US | disclosed |
| WO-2014153620-A1 | METHOD FOR GENERATING MATURE β-LIKE CELLS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2014-10-02 | — | — | WO | disclosed |
| US-8524774-B1 | Topical two step polytherapy for treatment of psoriasis and other skin disorders | CYMBIOTICS, INC. (US) | 2013-09-03 | — | — | US | disclosed |
| US-4258052-A | APPLYING TOPICALLY | YU RUEY J | 1981-03-24 | — | — | US | disclosed |