SCHEMBL11359698

SCHEMBL11359698

OC(=S)N(SC1CCCCC1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.43
LMNA P02545 2/20 0.43
ALDH1A1 P00352 5/20 0.36
KMT2A Q03164 4/20 0.36
RAB9A P51151 3/20 0.36
MEN1 O00255 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 2/20 0.36
PKM P14618 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MITF O75030 1/20 0.36
PAX8 Q06710 1/20 0.36
HTT P42858 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
FAAH O00519 1/20 0.34
PHGDH O43175 1/20 0.34
MGLL Q99685 1/20 0.34
ESR1 P03372 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.34
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11353342 0.83 ALDH1A1 (0.43) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11288778 0.83 ALDH1A1 (0.43) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11293022 0.83 ALDH1A1 (0.43) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11349789 0.82 LMNA (0.40) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11291463 0.81 ALDH1A1 (0.41) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11359679 0.80 ALDH1A1 (0.41) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11276466 0.79 ALDH1A1 (0.40) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11276019 0.79 ALDH1A1 (0.40) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11271271 0.77 KEAP1 (0.39) GAALMNAALDH1A1KMT2ARAB9A
SCHEMBL11358324 0.75 ALDH1A1 (0.38) GAALMNAALDH1A1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0008177-B1 VULCANIZABLE RUBBER COMPOSITIONS CONTAINING SUBSTITUTED CARBAMIC ACID ESTERS MONSANTO COMPANY (US) 1981-08-26 EP disclosed
EP-0008177-A1 Vulcanizable rubber compositions containing substituted carbamic acid esters MONSANTO COMPANY (US) 1980-02-20 EP disclosed
US-4156680-A Scorch inhibited vulcanizable rubber compositions containing carbamic acid esters MONSANTO COMPANY (US) 1979-05-29 US disclosed